TREMFYA withMe Program: for patients who are prescribed TREMFYA®

TREMFYA withMe is here to help guide you on your treatment journey—from cost and coverage support, to injection education, as well as a dedicated live person available for you. This is a hassle- and cost-free program for everyone*. Whether it's your first time on treatment or you're already on your treatment journey, we'll be right by your side.

You'll get a dedicated TREMFYA withMe Guide - a qualified healthcare professional ready to help. Along your treatment journey, the support you may need is just a phone call away. Here are just some of the ways your Guide can help:

  • Setting Expectations: You'll get information about your TREMFYA® treatment and you'll be guided along the way with educational support.
  • Prescription and Cost Support: You'll receive support to help you: verify your insurance coverage, understand how to fill your prescriptions, and look for options that could make your treatment more affordable.
  • Injection Support: Your doctor will review the injection process with you. Your doctor is the best person to help you understand what to expect. Your Guide is also available, after you have talked with your doctor, if you have questions about injections.
  • Stay on Track: You'll receive support to help you stay on track with your treatment, plus updates on your TREMFYA® treatment journey.

Sign up by visiting or learn more about TREMFYA withMe by calling 1-833-WITHME1 (833-948-4631), Monday through Friday, from 8:00 AM to 11:00 PM ET.

*Eligible patients over 18 with a prescription for approved on-label use. Eligibility criteria for some program components may vary.

Guides do not provide medical advice. Please ask your doctor any questions you might have about your disease and treatment.

If you haven't signed up for TREMFYA withMe, a Janssen CarePath Case Manager can:

  • Review your health plan benefits to help answer questions you may have about insurance coverage for TREMFYA®
  • Identify options that may help make TREMFYA® more affordable, if needed
  • Connect you with a nurse at Janssen Nurse Support to answer questions about treatment with TREMFYA®*
  • Offer treatment education support. We also invite you to learn more at
  • Work with your pharmacy to process and deliver your TREMFYA® medication to your home or your doctor’s office

*Janssen Nurse Support is limited to education about your Janssen medication, its administration, and/or the condition it treats. It is not intended to provide medical advice, replace a treatment plan you receive from your doctor or nurse, or serve as a reason for you to start or stay on treatment.

Need Help? Please call a Janssen CarePath Case Manager at 877-CarePath (877-227-3728), Monday-Friday, 8:00 AM to 8:00 PM ET. Multilingual phone support is available.

Get started with a Janssen CarePath Account

Sign Up or Log In to your personal Janssen CarePath Account, so you can learn about your insurance coverage for TREMFYA®; if eligible, enroll in the TREMFYA withMe Savings Program and manage program benefits; and find support to help you start and stay on track with your Janssen medication.

If your health plan does not approve TREMFYA® treatment

Sometimes you may not be able to obtain the medication that your doctor has prescribed for you. For example, your health plan might not cover the medication because it is not on the plan’s drug list (formulary) or the cost is higher than you think you should have to pay. In these situations, you and your doctor have the right to ask the health plan to explain its decision and to consider making the medication available to you as an exception to its policies.

Injection Support

A nurse is just a phone call away

Even after you’ve been trained by a healthcare professional to give yourself an injection, you may still have questions. If you haven't signed up for TREMFYA withMe, Janssen Nurse Support can help answer questions about giving yourself an injection at home, preparing your injection site prior to self-injecting, and properly disposing of your used syringe.

Connect with Janssen Nurse Support at 877-CarePath (877-227-3728), available Monday-Friday, 9:00 AM to 8:00 PM ET. At all other times, a nurse will typically return your call in 15 minutes.

Janssen Nurse Support is limited to education about your Janssen medication, its administration, and/or the condition it treats. It is not intended to provide medical advice, replace a treatment plan you receive from your doctor or nurse, or serve as a reason for you to start or stay on treatment.

Convenient Disposal of Used Devices

If you've received approval to inject at home and have been properly trained, you can use Safe Returns® as a simple, safe, and convenient way to dispose of your used devices—at no cost to you. When you sign up, you'll receive a certified Safe Returns® sustainable mail-back envelope in the mail, along with easy-to-follow mail-back instructions. To sign up for Safe Returns®, you can call 877-CarePath (877-227-3728) or fill out the enrollment form at

Health Insurance Open Enrollment Guide

Even if you keep the same health plan year to year, your benefits can change. This guide can help you review your coverage and make changes if needed during the open enrollment period so you can stay on treatment in the new benefit period, usually beginning January 1.

Get Open Enrollment Guide [PDF]

Get Open Enrollment Guide [PDF] (en español)

If you’re enrolled in Medicare and using Medicare insurance to pay for your medications, our Medicare Resource Guide provides important information to consider as you are selecting your insurance coverage.

Get Medicare Resource Guide [PDF]

Get Medicare Resource Guide [PDF] (en español)

Connecting with others in your community

Resources are available online that can offer support and help you connect with others who are living with your condition. These include local support groups, fundraising walks, outreach programs, online communities, and volunteer opportunities. The websites below can help you learn more about your condition and connect with others.

TREMFYA® Website
This website contains information about treatment with TREMFYA®. On this website, you can also get helpful information about your condition.

American Academy of Dermatology
The American Academy of Dermatology is dedicated to providing dermatologists with the information and resources they need to serve their patients. Patients can learn more about dermatologists and the conditions they treat.
Click here for Psoriatic Arthritis Information
Click here for Plaque Psoriasis Information

The Arthritis Foundation
The Arthritis Foundation offers guidance and support for those living with all forms of arthritis including psoriatic arthritis. Also available are tools, resources, and opportunities to get involved and connect to local support.

Arthritis Today
The online home of the Arthritis Foundation’s Arthritis Today magazine is a great source of tips and information for people living with all forms of arthritis, including psoriatic arthritis.

CreakyJoints is a non-profit organization that provides a support community for patients and their caregivers. CreakyJoints members receive newsletters, opportunities to participate in workshops, and special events and programs, which provide educational materials about psoriatic arthritis.

National Psoriasis Foundation
The National Psoriasis Foundation is a patient-driven, nonprofit organization that is the voice for the 5 million people affected by psoriatic diseases. The website’s mission is to improve lives through education, advocacy, and research.


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WHAT IS TREMFYA® (guselkumab)?

TREMFYA® is a prescription medicine used to treat adults with moderate to severe plaque psoriasis who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet or UV light).

TREMFYA® is a prescription medicine used to treat adults with active psoriatic arthritis.


What is the most important information I should know about TREMFYA®?

TREMFYA® is a prescription medicine that may cause serious side effects, including:

  • Serious Allergic Reactions. Stop using TREMFYA® and get emergency medical help right away if you develop any of the following symptoms of a serious allergic reaction:
  • fainting, dizziness, feeling lightheaded (low blood pressure)
  • swelling of your face, eyelids, lips, mouth, tongue or throat
  • trouble breathing or throat tightness
  • chest tightness
  • skin rash, hives
  • itching
  • Infections. TREMFYA® may lower the ability of your immune system to fight infections and may increase your risk of infections. Your healthcare provider should check you for infections and tuberculosis (TB) before starting treatment with TREMFYA® and may treat you for TB before you begin treatment with TREMFYA® if you have a history of TB or have active TB. Your healthcare provider should watch you closely for signs and symptoms of TB during and after treatment with TREMFYA®.

Tell your healthcare provider right away if you have an infection or have symptoms of an infection, including:

  • fever, sweats, or chills
  • muscle aches
  • weight loss
  • cough
  • warm, red, or painful skin or sores on your body different from your psoriasis
  • diarrhea or stomach pain
  • shortness of breath
  • blood in your phlegm (mucus)
  • burning when you urinate or urinating more often than normal

Do not take TREMFYA® if you have had a serious allergic reaction to guselkumab or any of the ingredients in TREMFYA®.

Before using TREMFYA®, tell your healthcare provider about all of your medical conditions, including if you:

  • have any of the conditions or symptoms listed in the section “What is the most important information I should know about TREMFYA®?
  • have an infection that does not go away or that keeps coming back.
  • have TB or have been in close contact with someone with TB.
  • have recently received or are scheduled to receive an immunization (vaccine). You should avoid receiving live vaccines during treatment with TREMFYA®.
  • are pregnant or plan to become pregnant. It is not known if TREMFYA® can harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if TREMFYA® passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of TREMFYA®?

TREMFYA® may cause serious side effects. See “What is the most important information I should know about TREMFYA®?

The most common side effects of TREMFYA® include: upper respiratory infections, headache, injection site reactions, joint pain (arthralgia), diarrhea, stomach flu (gastroenteritis), fungal skin infections, herpes simplex infections, and bronchitis.

These are not all the possible side effects of TREMFYA®. Call your doctor for medical advice about side effects.

Use TREMFYA® exactly as your healthcare provider tells you to use it.

Please read the full Prescribing Information, including Medication Guide for TREMFYA®, and discuss any questions that you have with your doctor.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.