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UPTRAVI® Website

UPTRAVI.com - This website contains information about treatment with UPTRAVI®. On this website, you can also get helpful information about your condition.

 

Authorization

Patient Authorization Form [PDF] - Allows you to authorize the use of your personal information for certain Janssen Patient Support Programs.

Patient Authorization Form [PDF] (en Español) - Allows you to authorize the use of your personal information for certain Janssen Patient Support Programs.

 

Patient Support

Dose Adjustment Phase Guide [PDF] - A guide that highlights important steps and information about titration with UPTRAVI®.

Steps to Getting Your Medicine [PDF] - A patient-friendly guide to the verification and delivery process.

Steps to Getting Your Medicine [PDF] (en Español) - A patient-friendly guide to the verification and delivery process.

 

Cost Support

Janssen CarePath Oral PAH Savings Program Overview [PDF] - Provides information on the Janssen CarePath Savings Program for UPTRAVI® and eligibility requirements for enrolling in the program.

 

Coverage

Medicare Open Enrollment Guide [PDF] - Even if you keep the same health plan, your benefits can change. This guide can help you review your coverage and make changes if needed during the open enrollment period so you can stay on treatment in the new benefit period.

Medicare Resource Guide [PDF] - Provides information on sources for cost support that may be available to patients enrolled in Medicare. Medicare Resource Guide [PDF] (en español).

Medicare Part D Resource for Patients [PDF] - Helps you understand the 4 phases of coverage (Deductible, Initial Coverage, Coverage Gap, and Catastrophic Coverage), and when you will enter the Coverage Gap (formerly known as the Donut Hole). Medicare Part D Resource for Patients [PDF] (en español).

Medicare Low-Income Subsidy (LIS) Brochure [PDF] - Offers information about extra help with prescription drug costs that is available to low-income residents of the United States enrolled in Medicare Prescription Drug Plans.

 

Questions? 866-228-3546

Monday–Friday, 8:00 AM–8:00 PM ET

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IMPORTANT SAFETY INFORMATION
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What is UPTRAVI®?

UPTRAVI® (selexipag) is a prescription medicine used to treat pulmonary arterial hypertension (PAH, WHO Group 1), which is high blood pressure in the arteries of your lungs.

UPTRAVI® can help delay (slow down) the progression of your disease and lower your risk of being hospitalized for PAH.

It is not known if UPTRAVI® is safe and effective in children.

IMPORTANT SAFETY INFORMATION

  • Do not take UPTRAVI® if you take gemfibrozil because this medicine may affect how UPTRAVI® works and cause side effects
  • Do not take UPTRAVI® if you are allergic to selexipag or any of the ingredients in UPTRAVI®
  • Before you take UPTRAVI®, tell your healthcare provider about all your medical conditions, including if you:
    • Have liver problems
    • Have narrowing of the pulmonary veins (veins in your lungs). This is called pulmonary veno-occlusive disease (PVOD)
    • Are pregnant or plan to become pregnant. It is not known if UPTRAVI® will harm your unborn baby
    • Are breastfeeding or plan to breastfeed. It is not known if UPTRAVI® passes into your breast milk. You and your doctor should decide if you will take UPTRAVI® or breastfeed. You should not do both
    • Are taking any other prescription or over-the-counter medicines, vitamins, or herbal supplements

What are the possible side effects of UPTRAVI®?

The most common side effects are:

  • Headache
  • Diarrhea
  • Jaw pain
  • Nausea
  • Muscle pain
  • Vomiting
  • Pain, redness or swelling at the injection site with UPTRAVI® for injection
  • Pain in arms or legs
  • Temporary reddening of the skin (flushing)
  • Joint pain
  • Low red blood cell count
  • Less appetite than usual
  • Rash

Talk to your doctor if you have a side effect that bothers you or does not go away. These are not all the possible side effects of UPTRAVI®. For more information, ask your doctor or pharmacist.

You may report side effects to FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Keep UPTRAVI® and all other medicines away from children.

What other medicines might interact with UPTRAVI®?

UPTRAVI® and other medicines may affect each other, causing side effects. Tell your doctor about all the medicines you are taking. Do not start any new medicine until you check with your doctor.

How should I take UPTRAVI®?

UPTRAVI® Tablets

  • Take UPTRAVI® exactly as your doctor tells you to take it. Usually, your doctor will have you take UPTRAVI® twice a day. Taking UPTRAVI® with food may help you tolerate UPTRAVI® better
  • Swallow UPTRAVI® tablets whole. Do not split, crush, or chew tablets
  • Tell your doctor if you have any form of liver disease. Your doctor may need to change your dose of UPTRAVI®
  • UPTRAVI® is measured in micrograms (mcg). Tablets come in the following strengths: 200, 400, 600, 800, 1000, 1200, 1400, and 1600 mcg

UPTRAVI® given by intravenous (IV) injection

  • Your healthcare provider will give you UPTRAVI® into your vein through an intravenous (IV) line
  • Your healthcare provider will decide how much UPTRAVI® for injection you will receive each day based on your current dose of UPTRAVI® tablets

Please see full Prescribing Information and Patient Product Information.

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