Staying on Track

Staying on Track

We understand how important it is for you to take your SIMPONI® medication just as your doctor prescribed. Janssen CarePath provides ongoing support to help you stay on track with your SIMPONI® treatment.

Tools to help you work with your doctor

Effective communication with your doctor is important to help with your treatment journey. Visit Simponi.com for tips on getting the most out of each office visit.

Convenient disposal of your used autoinjectors or syringes

Safe Returns® is a simple, safe, and convenient way to dispose of your used injection devices—at no additional cost to you. When you sign up, you’ll receive a Safe Returns® plastic disposal container in the mail, along with simple mail-back instructions.

For these approved indications: moderate to severe rheumatoid arthritis, active psoriatic arthritis, or active ankylosing spondylitis, click here to enroll in the Safe Returns® program

For the approved indication of moderate to severe ulcerative colitis, click here to enroll in the Safe Returns® program

Support, Encouragement, Treatment Reminders

Get medication and treatment reminders in the palm of your hand with Care4Today® Mobile Health Manager. More than just a self-directed reminder tool, it can help support and encourage you to manage your health. It was designed in consultation with patients, physicians, and pharmacists. The free app can be downloaded from the Apple App Store or from Google Play. Additional information is available at Care4Today.com.

Health Plan Open Enrollment Information

Even if you keep the same health plan year to year, benefits can change. The information in the Open Enrollment Brochure can help you review your coverage and make changes if needed to stay on treatment in your new benefit period, usually beginning January 1.

Get Open Enrollment Brochure

If you’re enrolled in Medicare and using Medicare insurance to pay for your medications, our Medicare Resource Guide provides important information to consider as you are selecting your insurance coverage.

Get Medicare Resource Guide

Connecting with others in your community

Resources are available online that can offer support and help you connect with others who are living with your condition. These include local support groups, fundraising walks, outreach programs, online communities, and volunteer opportunities. The Web sites below can help you learn more about your condition and connect with others.

SIMPONI® Web site
Simponi.com
This Web site contains information about treatment with SIMPONI®. On this Web site, you can get healthy living tips and helpful information about your condition.
 
Janssen Biotech, Inc., the maker of SIMPONI®, does not endorse and is not responsible for the content of any of the Web sites listed below or the services provided by these organizations. Clicking on any of the links below will take you to a Web site to which our privacy policy does not apply. We encourage you to read the privacy policy of every Web site you visit.
 
Advocacy Connector
AdvocacyConnector.com
This Web site provides links to a range of national and state-specific resources for rheumatology and gastroenterology. These resources include sites for clinical trials, financial support, legal assistance, and research. Links are provided for those seeking resources in areas such as pain management, caregiver support, and counseling, among a host of others. This list is updated regularly and is not comprehensive, so please check the site for specific content.
 
Arthritis Foundation
Arthritis.org
The mission of the Arthritis Foundation is to improve lives through leadership in the prevention, control, and cure of arthritis and related diseases. This Web site includes education and online community resources for people with arthritis and their families.
 
Arthritis Today
Arthritis.org/arthritis-today-magazine/
The online home of the Arthritis Foundation’s “Arthritis Today” magazine is a great source of tips and information for people living with arthritis.
 
CreakyJoints
CreakyJoints.org
CreakyJoints provides treatment information, advice from professionals, and public forums for people living with arthritis to share their experiences.
 
Crohn's & Colitis Foundation of America
CCFA.org
The Crohn's & Colitis Foundation of America is a nonprofit, volunteer-driven organization dedicated to finding the cure for Crohn's disease and ulcerative colitis. The Web site contains medical information, news, and events about digestive diseases.
 
National Psoriasis Foundation
Psoriasis.org
The National Psoriasis Foundation is a patient-driven, non-profit organization that is the voice for the 5 million people affected by psoriatic diseases, including psoriatic arthritis. The Web site’s mission is to improve lives through education, advocacy, and research.
 
Spondylitis Association of America
Spondylitis.org
The Spondylitis Association of America is the first and largest resource for people affected by spondylitis. The Web site's efforts help to advance education, research, and treatment for ankylosing spondylitis (AS) and related diseases. This site includes information and support for patients with AS and their families.

Now that you have begun the journey with your SIMPONI® treatment, please know we are here to help.

Janssen CarePath
Call: 877-CarePath (877-227-3728)
Monday-Friday, 8 AM to 8 PM ET

What is SIMPONI® (golimumab)?

SIMPONI® is a prescription medicine for adults with:

  • Moderate to severe rheumatoid arthritis (RA), with the medicine methotrexate (MTX)
  • Active psoriatic arthritis (PsA), alone or with the medicine MTX
  • Active ankylosing spondylitis (AS)
  • Moderately to severely active ulcerative colitis (UC) when certain other UC medicines have not worked well enough or cannot be tolerated, or if it is necessary to continue taking steroid medicines:
    • To begin helping some of your symptoms
    • In people who respond to SIMPONI®, to get their UC under control (induce remission) and keep UC under control (sustain remission)
    • To begin to improve the way the lining of your large intestine looks to your doctor during colonoscopy

MTX is used as directed.

For RA, PsA, and AS: SIMPONI® 50 mg is given as an injection under the skin (subcutaneous injection) once a month.

For UC: SIMPONI® begins with 3 starter injections under the skin (subcutaneous injection): Two 100-mg injections on the first day of treatment, followed by one 100-mg injection 2 weeks later. After these 3 starter injections, SIMPONI® requires one 100-mg injection every 4 weeks.

Once you and your doctor are comfortable with the self-injection process, you will inject SIMPONI® under the skin.

Important Safety Information For SIMPONI®

SERIOUS INFECTIONS

SIMPONI® (golimumab) is a prescription medicine. SIMPONI® can lower your ability to fight infections. There are reports of serious infections caused by bacteria, fungi, or viruses that have spread throughout the body, including tuberculosis (TB) and histoplasmosis. Some of these infections have been fatal. Your doctor will test you for TB before starting SIMPONI® and will monitor you for signs of TB during treatment. Tell your doctor if you have been in close contact with people with TB. Tell your doctor if you have been in a region (such as the Ohio and Mississippi River Valleys and the Southwest) where certain fungal infections like histoplasmosis or coccidioidomycosis are common.

You should not start SIMPONI® if you have any kind of infection. Tell your doctor if you are prone to or have a history of infections or have diabetes, HIV or a weak immune system. You should also tell your doctor if you are currently being treated for an infection or if you have or develop any signs of an infection such as:

  • fever, sweat, or chills

  • muscle aches

  • cough

  • shortness of breath

  • blood in phlegm

  • weight loss

  • warm, red, or painful skin or sores on your body

  • diarrhea or stomach pain

  • burning when you urinate or urinate more than normal

  • feel very tired

CANCER

Unusual cancers have been reported in children and teenage patients taking TNF-blocker medicines. For children and adults taking TNF blockers, including SIMPONI®, the chances for getting lymphoma or other cancers may increase. Hepatosplenic T-cell lymphoma, a rare and fatal lymphoma, has occurred mostly in teenage or young adult males with Crohn’s disease or ulcerative colitis who were taking other TNF blockers with azathioprine or 6-mercaptopurine. You should tell your doctor if you have had or develop lymphoma or other cancers.

Some people treated with SIMPONI® have developed certain kinds of skin cancer. If any changes in the appearance of your skin or growths on your skin occur during or after your treatment with SIMPONI®, tell your doctor.

USE WITH OTHER DRUGS

Tell your doctor about all the medications you take including ORENCIA (abatacept), KINERET (anakinra), ACTEMRA (tocilizumab), RITUXAN (rituximab), or another TNF blocker, or if you are scheduled to or recently received a vaccine. People taking SIMPONI® should not receive live vaccines or treatment with a weakened bacteria (such as BCG for bladder cancer).

HEPATITIS B INFECTION

Reactivation of hepatitis B virus has been reported in patients who are carriers of this virus and are taking TNF-blocker medicines, such as SIMPONI®. Some of these cases have been fatal. Your doctor should do blood tests before and after you start treatment with SIMPONI®. Tell your doctor if you know or think you may be a carrier of hepatitis B virus or if you experience signs of hepatitis B infection, such as:

  • feel very tired

  • dark urine

  • skin or eyes look yellow

  • little or no appetite

  • vomiting

  • muscle aches

  • clay-colored bowel movements

  • fevers

  • chills

  • stomach discomfort

  • skin rash

HEART FAILURE

Heart failure can occur or get worse in people who use TNF blockers, including SIMPONI®. If you develop new or worsening heart failure with SIMPONI®, you may need treatment in a hospital, and it may result in death. Your doctor will closely monitor you if you have heart failure. Tell your doctor right away if you get new or worsening symptoms of heart failure like shortness of breath, swelling of your lower legs or feet, or sudden weight gain.

NERVOUS SYSTEM PROBLEMS

Rarely, people using TNF blockers, including SIMPONI®, can have nervous system problems such as multiple sclerosis or Guillain-Barré syndrome. Tell your doctor right away if you have symptoms like vision changes, weakness in your arms or legs, or numbness or tingling in any part of your body.

IMMUNE SYSTEM PROBLEMS

Rarely, people using TNF blockers have developed lupus-like symptoms. Tell your doctor if you have any symptoms such as a rash on your cheeks or other parts of the body, sensitivity to the sun, new joint or muscle pain, becoming very tired, chest pain or shortness of breath, swelling of the feet, ankles, and/or legs.

LIVER PROBLEMS

Serious liver problems can happen in people using TNF blockers, including SIMPONI®. Contact your doctor immediately if you develop symptoms such as feeling very tired, skin or eyes look yellow, poor appetite or vomiting, or pain on the right side of your stomach.

BLOOD PROBLEMS

Low blood counts have been seen with people using TNF blockers, including SIMPONI®. If this occurs, your body may not make enough blood cells to help fight infections or help stop bleeding. Your doctor will check your blood counts before and during treatment. Tell your doctor if you have signs such as fever, bruising, bleeding easily, or paleness.

OTHER CONSIDERATIONS TO TELL YOUR DOCTOR

Tell your doctor if you are allergic to rubber or latex. The needle cover contains dry natural rubber.

Tell your doctor if you are pregnant, planning to become pregnant or are breastfeeding or have a baby and were using SIMPONI® during pregnancy. Tell your baby’s doctor before your baby receives any vaccine because of an increased risk of infection for up to 6 months after birth.

ALLERGIC REACTIONS

Allergic reactions can happen in people who use TNF-blocker medicines, including SIMPONI®. Tell your doctor if you have any symptoms of an allergic reaction while taking SIMPONI® such as hives, swollen face, breathing trouble, or chest pain. Some reactions can be serious and life-threatening.

Common side effects of SIMPONI® include: upper respiratory tract infection, reaction at site of injection, and viral infections.

PSORIASIS

New or worse psoriasis symptoms may occur. Tell your doctor if you develop red scaly patches or raised bumps that are filled with pus.

Please read the full Prescribing Information and Medication Guide for SIMPONI® and discuss any questions you have with your doctor.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

042501-151027