Your Personal Account for online access to:

  • Check your insurance coverage
  • Enroll in Savings Program
  • Sign up for treatment reminders

Paying for PREZCOBIX®

Paying for PREZCOBIX®

Helping make PREZCOBIX® more affordable for eligible patients

At Janssen, we don't want cost to get in the way of treatment you need. We can help you explore options to lower your out-of-pocket cost for PREZCOBIX®. No matter what type of insurance you have – or even if you don't have insurance – Janssen CarePath can help explain your medication insurance coverage and benefits, and help find programs that may help you pay for PREZCOBIX®.

If you use commercial or private health insurance to pay for your medication:

The Janssen CarePath Savings Program for PREZCOBIX® may provide instant savings on your out-of-pocket medication costs for PREZCOBIX® if you have commercial or private health insurance. If you are eligible, you will pay $0 each time you fill your prescription for PREZCOBIX®. The program pays deductible, co-pay, and/or co-insurance up to a $7,500 maximum benefit per calendar year. Not valid for Medicaid, Medicare, or similar state or federal programs. Click here for full eligibility requirements.

If you are eligible for Janssen CarePath Savings Program, go to your personal Janssen CarePath Account and enroll in the program:

If your pharmacy is unable to process your Savings Card, you have two options:

  • In your Janssen CarePath Account, you can navigate to the Savings Program tab, and click on "Savings Program Request" and follow the instructions to complete the process online.
  • If you don't have a Janssen CarePath Account, you can complete, sign and return the rebate form (instructions on form), with required proof of purchase, to receive your rebate benefit. Click here to get the rebate form.

Call a Janssen CarePath Care Coordinator at 877-CarePath (877-227-3728) for more information.

If you are using government insurance to pay for PREZCOBIX®: provides information on affordability programs and up-to-date information about independent foundations that may have funding available to help you with medication costs for PREZCOBIX®.

If you are enrolled in Medicare and using Medicare insurance to pay for your medication, our Medicare Resource Guide provides additional information on sources for cost support that may be available for you.

Get Medicare Resource Guide

Call a Janssen CarePath Care Coordinator at 877-CarePath (877-227-3728) for more information.

If you have no health insurance or no coverage for PREZCOBIX®: provides information on affordability programs and up-to-date information about independent foundations that may have funding available to help you with medication costs for PREZCOBIX®.

Call a Janssen CarePath Care Coordinator at 877-CarePath (877-227-3728) for more information.

Other Resources

Johnson & Johnson Patient Assistance Foundation, Inc. (JJPAF) provides free prescription medications to eligible individuals without insurance coverage for their medications and those who do not have adequate financial resources to pay for them. To see if you might qualify for assistance, please contact a JJPAF program specialist at 1-800-652-6227 (9 AM to 6 PM ET) or visit the foundation Web site at


PREZCOBIX® is a prescription HIV-1 (Human Immunodeficiency Virus 1) medicine always used with other antiretroviral medicines to treat HIV-1 infection in adults. HIV is the virus that causes AIDS (Acquired Immune Deficiency Syndrome). PREZCOBIX® contains prescription medicines PREZISTA® (darunavir) and TYBOST® (cobicistat). PREZCOBIX® does not cure HIV-1 infection or AIDS. You must keep taking HIV-1 medicines to control HIV-1 infection and decrease HIV-related illnesses. PREZCOBIX® should be taken once daily with food.

Important Safety Information For PREZCOBIX®

What is the most important information I should know about PREZCOBIX®?

  • PREZCOBIX® may cause liver problems which may be life-threatening. Tell your healthcare provider right away if you have any symptoms such as: 
    • Dark (tea-colored) urine
    • Yellowing of your skin or the whites of your eyes
    • Pale-colored stools (bowel movements)
    • Nausea
    • Vomiting
    • Pain or tenderness on your right side below your ribs
    • Loss of appetite
  • PREZCOBIX® may cause severe or life-threatening skin reactions or rashesStop taking PREZCOBIX® and call your healthcare provider right away if you develop any skin changes with symptoms below: 
    • Fever
    • Tiredness
    • Muscle or joint pain
    • Blisters or skin lesions
    • Mouth sores or ulcers
    • Red or inflamed eyes, like "pink eye" (conjunctivitis)
  • PREZCOBIX®, when taken with some other medications, can cause new or worse kidney problems, including kidney failure. 

Who should not take PREZCOBIX®?

  • Do not take PREZCOBIX® with any of the following medicines: alfuzosin (Uroxatral®), carbamazepine (Carbatrol®, Epitol®, Equetro®, Tegretol®, Tegretol-XR®, Teril®), cisapride (Propulsid®), colchicine (Colcrys®, Mitigare®, if you have liver or kidney problems), dronedarone (Multaq®), elbasvir and grazoprevir (Zepatier®), dihydroergotamine (D.H.E.45®, Migranal®), ergotamine tartrate (Cafergot®, Ergomar®, Ergostat®, Medihaler®, Migergot®, Wigraine®, Wigrettes®), methylergonovine (Methergine®), lovastatin or a product that contains lovastatin  (Altoprev®, Advicor®, Mevacor®), lurasidone (Latuda®), oral midazolam (Versed®), phenobarbital (Luminal®), phenytoin (Dilantin®, Dilantin-125®, Phenytek®), pimozide (Orap®), ranolazine (Ranexa®), rifampin (Rifadin®, Rifater®, Rifamate®, Rimactane®), sildenafil (Revatio®) when used for pulmonary arterial hypertension (PAH), simvastatin or a product that contains simvastatin (Simcor®, Vytorin®, Zocor®), St. John’s Wort (Hypericum perforatum) or a product that contains St. John’s Wort, or triazolam (Halcion®).
  • Serious problems can happen if you take any of these medicines with PREZCOBIX®.

What should I tell my healthcare provider before taking PREZCOBIX®?

  • Tell your healthcare provider if you:
    • have liver problems, including hepatitis B or hepatitis C, have kidney problems, are allergic to sulfa (sulfonamide), have diabetes, have hemophilia, or have any other medical condition
    • are pregnant (if you become pregnant while taking PREZCOBIX®), breastfeeding, or plan to become pregnant or breastfeed. It is unknown if PREZCOBIX® will harm your unborn baby.
  • Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Some medicines interact with PREZCOBIX®. Keep a list of your medicines to show your healthcare provider and pharmacist. Do not start taking a new medicine without telling your healthcare provider.

What are the possible side effects of PREZCOBIX®?

PREZCOBIX® may cause serious side effects including:

  • Diabetes and high blood sugar
  • Changes in body fat can happen in people taking HIV-1 medications
  • Immune system changes can happen in people who start HIV medications
  • Increased bleeding can occur in people with hemophilia who are taking PREZCOBIX® 

The most common side effects are:

  • Diarrhea
  • Nausea
  • Rash
  • Headache
  • Stomach area (abdominal) pain
  • Vomiting

These are not all the possible side effects of PREZCOBIX®. Tell your healthcare provider if any side effect bothers you or does not go away. For more information, ask your healthcare provider.

You are encouraged to report negative side effects of prescription drugs to the FDA.

Visit or call 1-800-FDA-1088

You may also report side effects to Janssen Products, LP at 1-800-JANSSEN (1-800-526-7736).

Please read full Product Information