Medicaid Fee-for-Service

Medicaid Fee-for-Service

Help for your patients in need

Medicaid Fee-for-Service is a state-specific program. Coverage may depend on the indication as well as other factors. As this information varies by state, it is important to contact the state agency directly or consult its Web site to obtain product-specific coverage and other information.

Disclaimer: Janssen Products, LP, the maker of SYLVANT®, does not endorse and is not responsible for the content on any of the Web sites listed below. Clicking on any of the links below will take you to a Web site to which this privacy policy does not apply. We encourage you to read the privacy policy of every Web site you visit.

Blank Entry: Not found in the public domain
Brand: A patented drug listed in PDL or supporting documents
Covered: Drug is listed in PDL or supporting documents
Preferred: Refers to the coverage level of a drug

State Preferred Drug List (PDL)* Status Prior Authorization Required
Alabama Covered  
Alaska Covered Yes
Arizona   Yes
Arkansas Covered Yes
California Covered Yes
Colorado   Yes
Connecticut   Yes
Delaware   Yes
District of Columbia   Yes
Florida   Yes
Georgia   Yes
Hawaii Covered  
Idaho   Yes
Illinois Brand Yes
Indiana   Yes
Iowa   Yes
Kansas   Yes
Kentucky    
Louisiana   Yes
Maine Covered  
Maryland Covered  
Massachusetts Covered Yes
Michigan Covered Yes
Minnesota Covered Yes
Mississippi   Yes
Missouri Covered  
Montana   Yes
Nebraska    
Nevada   Yes
New Hampshire Covered  
New Jersey Covered  
New Mexico Covered  
New York   Yes
North Carolina Covered Yes
North Dakota Covered  
Ohio Covered Yes
Oklahoma Covered Yes
Oregon Covered Yes
Pennsylvania Covered  
Rhode Island   Yes
South Carolina Covered Yes
South Dakota   Yes
Tennessee   Yes
Texas   Yes
Utah   Yes
Vermont   Yes
Virginia   Yes
Washington   Yes
West Virginia   Yes
Wisconsin   Yes
Wyoming   Yes

* The title for each state's Medicaid Fee-for-Service drug list may vary (e.g., Prescription Drug List, Contract Drug List).

R4

Indication

SYLVANT® (siltuximab) is indicated for the treatment of patients with Multicentric Castleman's Disease (MCD) who are human immunodeficiency virus (HIV) negative and human herpesvirus-8 (HHV-8) negative.

Limitation of Use. SYLVANT® was not studied in patients with MCD who are HIV-positive or HHV-8 positive because SYLVANT® did not bind to virally produced IL-6 in a nonclinical study.

Important Safety Information For SYLVANT®

CONTRAINDICATIONS – Severe hypersensitivity reaction to siltuximab or any of the excipients in SYLVANT®.

Concurrent Active Severe Infections – Do not administer to patients with severe infections until the infection resolves. SYLVANT® may mask signs and symptoms of acute inflammation including suppression of fever and of acute phase reactants such as C-reactive protein (CRP). Monitor patients closely for infections. Institute prompt anti-infective therapy and do not administer further SYLVANT® until the infection resolves.

Vaccinations – Do not administer live vaccines to patients receiving SYLVANT® because interleukin-6 (IL-6) inhibition may interfere with the normal immune response to new antigens.

Infusion Related Reactions and Hypersensitivity – Stop the infusion if the patient develops signs of anaphylaxis. Discontinue further therapy.

Stop the infusion if the patient develops mild to moderate infusion reactions. If the reaction resolves, the infusion may be restarted at a lower infusion rate. Consider medicating with antihistamines, acetaminophen, and corticosteroids. Discontinue SYLVANT® if the patient does not tolerate the infusion following these interventions.

Administer SYLVANT® in a setting that provides resuscitation equipment, medication, and personnel trained to provide resuscitation.

Gastrointestinal (GI) Perforation – Use with caution in patients who may be at increased risk for GI perforation. Promptly evaluate patients presenting with symptoms that may be associated with or suggestive of GI perforation.

Adverse Reactions – The most common adverse reactions (>10% compared to placebo) in the MCD clinical trial were pruritus, increased weight, rash, hyperuricemia, and upper respiratory tract infection.

Drug Interactions Cytochrome P450 (CYP450) Substrates – Upon initiation or discontinuation of SYLVANT®, in patients being treated with CYP450 substrates with narrow therapeutic index, perform therapeutic monitoring of effect (e.g., warfarin) or drug concentration (e.g., cyclosporine or theophylline) as needed and adjust dose. Exercise caution when SYLVANT® is co-administered with CYP3A4 substrate drugs where a decrease in effectiveness would be undesirable (e.g., oral contraceptives, lovastatin, atorvastatin).

Please click here to read full Prescribing Information for SYLVANT®.

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