Helping Patients Afford SYLVANT®
Support for Patients Using Commercial or Private Insurance
Janssen CarePath Savings Program for SYLVANT®
Your eligible patients will pay just $5 for each infusion, with a $20,000 maximum program benefit each calendar year. The Janssen CarePath Savings Program provides financial assistance to help patients with their out-of-pocket costs on their SYLVANT® medication, including: deductible, co-payment, and coinsurance costs. Eligible patients must use commercial or private health insurance that covers a portion of their medication costs for SYLVANT®. Patients using Medicare, Medicaid, or other federally funded programs to pay for SYLVANT® medication are not eligible to participate.
To learn more about the Janssen CarePath Savings Program, click here for full eligibility requirements.
Get your eligible patients started today. Visit the Janssen CarePath Provider Portal to create an account and you can:
- Enroll your eligible, commercially insured patients in the Janssen CarePath Savings Program
- Upload Explanation of Benefit (EOB) forms from your patients' insurance providers
- Review your patients' available benefit
- View patient transactions
- Receive timely alerts and program updates
Patients can also create their own Janssen CarePath Account where they can enroll in the Janssen CarePath Savings Program, learn about their insurance coverage for SYLVANT®, and sign up for personalized treatment reminders. Encourage your patient to sign up today at MyJanssenCarePath.com.
Support for patients using government insurance or patients without insurance coverage
JanssenPrescriptionAssistance.com provides information on affordability programs and up-to-date information about independent foundations that may have funding available to help you with medication costs for SYLVANT®.
Johnson & Johnson Patient Assistance Foundation, Inc. (JJPAF) provides free prescription medications to eligible individuals without insurance coverage for their medications and those who do not have adequate financial resources to pay for them. To see if they might qualify for assistance, please have your patient contact a JJPAF program specialist at 1-800-652-6227 (9 AM to 6 PM ET) or visit the foundation Web site at www.JJPAF.org.
SYLVANT® (siltuximab) is indicated for the treatment of patients with Multicentric Castleman's Disease (MCD) who are human immunodeficiency virus (HIV) negative and human herpesvirus-8 (HHV-8) negative.
Limitation of Use. SYLVANT® was not studied in patients with MCD who are HIV-positive or HHV-8 positive because SYLVANT® did not bind to virally produced IL-6 in a nonclinical study.
CONTRAINDICATIONS – Severe hypersensitivity reaction to siltuximab or any of the excipients in SYLVANT®.
Concurrent Active Severe Infections – Do not administer to patients with severe infections until the infection resolves. SYLVANT® may mask signs and symptoms of acute inflammation including suppression of fever and of acute phase reactants such as C-reactive protein (CRP). Monitor patients closely for infections. Institute prompt anti-infective therapy and do not administer further SYLVANT® until the infection resolves.
Vaccinations – Do not administer live vaccines to patients receiving SYLVANT® because interleukin-6 (IL-6) inhibition may interfere with the normal immune response to new antigens.
Infusion Related Reactions and Hypersensitivity – Stop the infusion if the patient develops signs of anaphylaxis. Discontinue further therapy.
Stop the infusion if the patient develops mild to moderate infusion reactions. If the reaction resolves, the infusion may be restarted at a lower infusion rate. Consider medicating with antihistamines, acetaminophen, and corticosteroids. Discontinue SYLVANT® if the patient does not tolerate the infusion following these interventions.
Administer SYLVANT® in a setting that provides resuscitation equipment, medication, and personnel trained to provide resuscitation.
Gastrointestinal (GI) Perforation – Use with caution in patients who may be at increased risk for GI perforation. Promptly evaluate patients presenting with symptoms that may be associated with or suggestive of GI perforation.
Adverse Reactions – The most common adverse reactions (>10% compared to placebo) in the MCD clinical trial were pruritus, increased weight, rash, hyperuricemia, and upper respiratory tract infection.
Drug Interactions – Cytochrome P450 (CYP450) Substrates – Upon initiation or discontinuation of SYLVANT®, in patients being treated with CYP450 substrates with narrow therapeutic index, perform therapeutic monitoring of effect (e.g., warfarin) or drug concentration (e.g., cyclosporine or theophylline) as needed and adjust dose. Exercise caution when SYLVANT® is co-administered with CYP3A4 substrate drugs where a decrease in effectiveness would be undesirable (e.g., oral contraceptives, lovastatin, atorvastatin).
Please click here to read full Prescribing Information for SYLVANT®.